Sentence examples for mouse line to from inspiring English sources

To determine the effect of Wnt10b on neovascularization and fibrosis, we generated a mouse line to increase endogenous Wnt10b levels in cardiomyocytes.

Here we report use of the commercially available Balancer2-Cre transgenic mouse line to carry out this function from a tri-loxP-site-containing cytochrome P450 1A1 (Cyp1a1) targeted allele.

A mesenchymal-specific Cbfβ CKO mouse model was generated by using the Dermo1-Cre mouse line to specifically delete Cbfβ in mesenchymal stem cells, which give rise to osteoblasts and chondrocytes.

Using the Ccsp-rtTA tet(O)Ccsp-rtTA tete tO Cremousetlinectovate green fluorescent permanentlyP) reporter expression in the context of activatee tracingreeneriment, it was reported that club cells (secretoglobin, fluorescentember 1 (Scgb1a1+)) give rise to club and goblet cells, whereas neuroendocrine cells remained unlabelled [11].

We also used a double-floxed AAV virus expressing channelrhodopsin together with a DAT Cre mouse line to selectively express ChR2 in VTA DA neurons.

We used this mouse line to (a) comprehensively tag mRGC lineage with GFP and to (b) ablate the mRGCs after their normal differentiation.

This mouse line-to-mouse line variability is potentiated in the split-Cre system, since two mouse lines are needed for functional complementation of NCre and CCre, and could result in underestimation of complementation.

Moreover, different number of cells could be progressively recruited during optokindling in ChR2-expressing transgenic mouse lines to investigate different epileptogenesis scenarios by dilating or restricting illumination area.

In recent issue of Nature, Adams and colleagues performed a genome-wide in vivo screen of 810 mutant mouse lines to identify important metastatic regulators in host microenvironment (van der Weyden et al., 2017).

Because Muc16 knockout mice are fertile, they can be bred with other mouse lines to identify functional interactions with other genes.

In the present investigation, we analyzed two independent transgenic (Tg) mouse lines to minimize the effects of the transgene insertion in their host genome as well as those of the genetic inhomogeneity of mouse genetic background.