Sentence examples for mouse line recapitulates from inspiring English sources
We have included a figure supplement to demonstrate that our Slc17a7-IRES-Cre mouse line recapitulates the expression of the Slc17a7 gene.
Similarly MmURE2 transgenic mouse lines recapitulate endogenous Dlx1/Dlx2 expression in this domain [ 18].
We have established an E-cadherin/p53 double conditional knockout (DCKO) mouse line that recapitulates human DGC morphologically and molecularly.
The reduced viability and blood phenotype (described later) of this S1PL−/− gene-trap line was recapitulated in another S1PL knockout mouse line generated by homologous recombination in which exons 7 8 were replaced by a cre-lox selection cassette (data not shown).
Therefore, the tert-deficient zebrafish line recapitulates the mechanisms of age in telomerase-deficient mice and individuals with DC (Armanios et al., 2005; Knudson et al., 2005; Vulliamy et al., 2004).
Recently, a new mutant mouse line lacking the orphan G protein-coupled receptor GPR-88 was reported to recapitulate hyperactivity-related ADHD-like symptoms (Quintana et al, 2012), further offering novel molecular mechanisms and molecular targets for ADHD research.
We demonstrate here that strain-related Sost down-regulation in cells of the human osteoblastic Saos2 cell line recapitulates in vitro, in terms of time, that stimulated in osteocytes by loading of the mouse tibia in vivo [9].
This mouse line was designated as ΔCS.
We generated the Aldh1b1tm1lacZ mouse line (ESM Fig. 1 a, b) and analysed pancreas development in the Aldh1b1tm1lacZ null embryos in which Lacz expression recapitulated expression in the pancreas (ESM Fig. 1 c h).
The Fmr1-mouse line does not recapitulate all of the main core and secondary ASD symptoms, but still can be useful to elucidate the neurobiological mechanisms underlying specific ASD-like endophenotypes.
Ins2 knock-in mouse lines have also been generated [ 25], but are similarly expected to recapitulate endogenous expression and result in ectopic expression in brain.
