Sentence examples for mouse line prevented from inspiring English sources
Similar to 129B6 mice, complete Bax deficiency in the DBA/2J mouse line prevented RGC soma death during glaucoma and after ONC (Libby et al., 2005a).
The apparent discrepancy between our results and the previous findings by Uyttendaele and colleagues [ 13] (who showed that overexpressing Notch4 in the mouse mammary epithelial TAC-2 cell line prevented branching morphogenesis in response to hepatocyte growth factor or transforming growth factor beta) underscores the importance of the experimental systems utilized.
Furthermore, administration of TAE684 in mice after injection of NPM ALK-positive ALCL cells (Karpas 299 cell liNPM ALK-positivevelopment of diseALCLand inducellsegression of pre-induced ALCL [ 142].
Taking advantage of the potential aspects of this double-transgenic mouse line, numerous studies have used this particular AD mouse model to investigate emergent therapies to prevent and/or reduce the neuropathological features of AD.
The wild-type human ADAM10 gene, in a mouse line carrying hAPP with the London mutation, increased the alpha-cleavage of APP, reduced the concentration of Aβ peptide, and prevented the formation of Aβ peptide deposits.
We termed this mouse line IL-1R1-restore (IL-1R1r).
This mouse line was designated as ΔCS.
Consistent with this finding, forced expression of ITM2A in the mouse mesenchymal stem cell line C3H10T1/2 prevented chondrogenic induction.
In line with these findings, ectopic expression of E-cadherin in a transgenic mouse model prevented tumor cell invasion and metastasis [ 7].
Here, we have used a gene targeting approach to create two mouse lines carrying internally rearranged exons of Lrp1b that are predicted to truncate the protein closer to the N-terminus and to prevent normal trafficking through the secretary pathway.
Compared with the wild-type mouse, they found that 15 mutant mouse lines showed significantly decreased pulmonary metastatic foci and 8 mutant mouse lines increased.
