Sentence examples for mouse leukemia lines from inspiring English sources

The analogs were tested for their antiproliferative activity against the cells of human breast cancer lines T47D and MCF7 as well as human and mouse leukemia lines, HL-60 and WEHI-3, respectively.

The NCI offered screening in animals and the ability to follow activities in cell lines derived from the animals (originally mouse leukemia lines), which then developed into screening against mouse lines and follow-up in immunologically compromised mice with implanted human cell lines.

Two recent publications have reported that gramisterol isolated from the rice bran extract displayed not only anti-cancerous activity against the mouse leukemia cell line, but also anti-tumor and immune enhancing activities against acute myelogenous leukemia (Suttiarporn et al. 2015; Somintara et al. 2016).

A previous study in a mouse leukemia cell line demonstrated that AZA incorporated into RNA and DNA at a ratio of approximately 85∶15, respectively [4].

Here we use epigenomic tools to simultaneously interrogate chromatin modifications and DNA methylation in a mouse leukemia cell line, L1210.

Similar results were observed in the WEHI-3B mouse leukemia cell line and to a lesser degree in mouse embryonic fibroblasts (MEFs).

We first performed chromatin ChIP-chip on the mouse leukemia cell line, L1210, with antibodies detecting either acetyl-H3K9 or dimethyl-H3K9.

We selected a single mouse leukemia cell line, L1210, in this study and conclusions drawn in this system will need to be validated in other mammalian cells.

In addition, an impairment of DNA and histone modifications has been observed in a mouse leukemia cell line, L1210, where an inverse relationship in the regulation of the silencing of candidate genes was reported [ 31].

Blast cells from patients with AML and a mouse leukemia cell line showed reduced B7-H1 protexpressionsion after exposure to MEK inhibitors, confirming that MEK is an important regulator of B7-H1 expressinn in leukemic cells (Fig.  5).

Mouse leukemia cell line L1210 (American Type Culture Collection, Manassas, VA) was grown in Dulbecco's modified Eagle's medium (Cellgro, Herndon, VA) plus 10% FBS in plastic tissue culture plates in a humidified atmosphere containing 5% CO2 at 37°C.