Sentence examples for mouse leukemia cells from inspiring English sources
Dansylated polytheonamide mimic (2) is an ion channel peptide which displays potent cytotoxicity against P388 mouse leukemia cells (IC50 = 12 nM).
These secosteroids inhibited proliferation and induced erythroid differentiation of K562 human chronic myeloid and MEL mouse leukemia cells with 20(OH)D3 and 20,23 OH 2D3 being either equipotent or slightly less potent than 1,25(OH)2D3, while 1,20(OH)2D3, pD and pL compounds were slightly or moderately less potent.
A previous report showed that TFP enhanced G2-M arrest in mouse leukemia cells exposed to bleomycin.
OP-A was shown to induce apoptosis in mouse leukemia cells and potently inhibit human cancer cell growth, but the precise mechanisms of action have remained unclear.
Finnon et al. [ 23] suggested that up-regulation of telomerase activity by x-rays in mouse leukemia cells was related to the transcription of telomerase-positive regulator proteins.
Specifically, we demonstrate an inverse relationship between DNA methylation and histone acetylation in regulating transcription of these genes in mouse leukemia cells.
Two recent publications have reported that gramisterol isolated from the rice bran extract displayed not only anti-cancerous activity against the mouse leukemia cell line, but also anti-tumor and immune enhancing activities against acute myelogenous leukemia (Suttiarporn et al. 2015; Somintara et al. 2016).
A previous study in a mouse leukemia cell line demonstrated that AZA incorporated into RNA and DNA at a ratio of approximately 85∶15, respectively [4].
Here we use epigenomic tools to simultaneously interrogate chromatin modifications and DNA methylation in a mouse leukemia cell line, L1210.
Similar results were observed in the WEHI-3B mouse leukemia cell line and to a lesser degree in mouse embryonic fibroblasts (MEFs).
We selected a single mouse leukemia cell line, L1210, in this study and conclusions drawn in this system will need to be validated in other mammalian cells.
