Sentence examples for mouse led to from inspiring English sources

Specific knockdown of Pcsk9 mRNA led to embryonic death at 4 days after fertilization in zebrafish [54], and complete knockout of Pcsk9 in mouse led to a ∼50% reduction in circulating levels of LDL cholesterol, but did not result in a lethal phenotype [55].

It remains an interesting historical artefact that the extreme susceptibility of the lab mouse led to ROP kinase discovery.

Strikingly, haploid insufficiency in mouse led to increased tumor appearances, of mainly large B cell lymphomas [ 13].

Treatment with RA antagonist in mouse led to randomization of heart looping and perturbed sideness of node [ 107].

injections of CRAd-S-pk7 CRAd-S-pk7 CRAd-S-pk7ed to a 90% of long-term survivors (>90 days) (LTS).

In therapy studies, a single dose of 90Y-A33 IgG (250 microCi per mouse) or 90Y-A33 TFM (300 microCi per mouse) led to complete regression of 2-week-old tumour xenografts with long-term tumour-free survivors.

Loss of function of this gene in mouse leads to a failure of hindlimb formation22,23 as well as strong pleiotropic defects in lung25 and placental development22.

Targeted deletion of PTEN in the mouse leads to constitutive activation of the PI3K/AKT pathway.

Genetic ablation of Scleraxis in the mouse leads to defective differentiation of limb muscle tendons [31].

As such, increased dosage of p44 in the mouse leads to accelerated aging and short lifespan.

The researchers found that inactivating the PTEN gene in mice led to the formation of the malignant tumor associated with BRCA1 mutations.