Sentence examples for mouse knockout model from inspiring English sources

We also performed Creb1 immunohistochemistry on sections of Creb1−/− lungs to validate our mouse knockout model.

We observed that complex II-dependent respiratory capacity is upregulated in matrix arm, subcomplex 1λ subunit dysfunction, as is consistent with a mouse knockout model of the subcomplex 1λ NDUFsubunitnit [15].

Presumably, since the mouse knockout model constitutes a null mutation for the mouse Cox-2 gene and results in a phenotype that is similar to the canine RD model, it is likely that the changes in the promoter region of the canine Cox-2 results in reduced amounts of Cox-2 protein.

10.7554/eLife.06358.005 Figure 2. Progressive RGS7 loss in the ON-BC neurons of a conditional mouse knockout model (cDKO).

Subsequent work using a mouse knockout model supported the role of ME1 in determining susceptibility to T2D.

This reasoning may explain, in part, why loss of PRG4 (lubricin) expression in a mouse knockout model leads to precocious wear only in mature joints [51].

Mouse knockout models have shown that heat shock transcription factor-1 (HSF1) is the key regulator of the HSR [1] [3].

Despite the very high degree of similarity between p63 and p73, mouse knockout models reveal distinct and non-redundant physiological roles.

However, delays have been encountered in generating mouse knockout models, and therefore there remain gaps in the information that urgently need bridging.

Sauvageau et al. recently generated mouse knockout models for two of these intergenic lncRNA loci, linc-Brn1a, and linc-Brn1b.

Mouse knockout models of Sulfatase 1 or Sulfatase 2 display a normal phenotype by nearly all criteria examined [ 9].