Sentence examples for mouse knee induced from inspiring English sources

Recently, we showed that intra-articular injection of BCP crystals into mouse knee induced cartilage degradation along with synovial inflammation [ 31].

VEGF has been implicated in OA pathogenesis since injection of VEGF into mice knees induced OA [ 34] and VEGF immunolocalisation correlated with cartilage destruction in several experimental animal models [ 35].

Injection of IL-17 into a mouse knee joint induces cartilage degradation, and IL-17 overexpression induces bone erosion and cartilage degradation [ 12].

A single injection of IL-17 into a normal mouse knee joint induces inflammatory arthritis [ 25].

Prolonged expression of mIL-1β in mice knee joints induced a severe arthritis in WT animals, exhibiting pathophysiologic changes resembling those in human RA.

Immunohistochemistry analysis of mouse knee sections of surgically induced OA and sham control (with Osteoarthritis Research Society International scores of 5 and 0, respectively) revealed that phosphorylated LKB1 and AMPKα were concomitantly decreased in mouse OA knee cartilage, compared with the sham control.

Previous studies have shown that hydrogen peroxide, when injected into mouse knee joints, was able to induce considerable chondrocyte death, which might be induced by apoptosis [ 42].

Furthermore, Davidson et al. find that the increased expression of Bmp2 does not exacerbate the degenerative condition of articular cartilage that has been induced by the DMM in mouse knee joints.

Flt3L has been shown to accumulate in RA SF and induces arthritis when injected into healthy mouse knee joints.

We investigated whether β-tryptase has proinflammatory actions in the mouse knee and specifically whether a tryptase inhibitor can modulate experimentally induced chronic joint inflammation.

Local injection of IL-1β into mouse knee joints resulted in the destabilization of joint homeostasis by inducing a catabolic shift in the articular cartilage [ 35].