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Distribution patterns of (R -[11C]PAQ compaR -[11C]PAQracomparedre very similar, exceptoin the mouse kidney wheracematepreciaree difference in uptake was observery(Figure 2C,F).
We have already shown that one of the vertebrate orthologues of the tio/ tsh genes, Tshz3, is expressed in the ureteric mesenchyme around the ureteric duct of embryonic mouse kidney, where it is required for the differentiation of smooth muscle (SM) cells (Caubit et al., 2008).
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To establish βarr2 targeting to PC in vivo, distribution of βarr2 was analyzed in mouse kidney sections (Figure 4F), where PCs are located at the luminal side (Lu) of tubular epithelial cells [22].
This trend was also observed for mouse kidney and mouse liver where the overlap was 3.7 times more than the expected (observed = 31, expected = 9, q = 1.05 × 10-9).
A recent gene expression microarray analysis in mice demonstrated that NCKX3 is expressed in the kidney, where it is primarily localized in the basolateral layer of the distal convoluted tubules, with no detectable expression in the glomerulus and proximal convoluted tubules, thus participating in active calcium transport in the kidney [40].
In contrast to humans where TRPM3 shows a high expression in kidney [ 17], mouse kidney did not reveal extensive expression of TRPM3.
In mice, KIM-1 was found upregulated in polycystic kidney disease especially in regions of the kidney where fibrosis takes place [ 150].
Mouse kidney progenitor cell.
A conceptual developmental framework has emerged for the mouse kidney.
They are histologically regarded as a normal finding in the mouse kidney tissue.
Autoradiography was performed to qualitatively measure relative 64Cu intensity in mouse kidney sections.
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