Sentence examples for mouse kidney development from inspiring English sources

Unlike human kidney development, mouse kidney development continues postnatally.

Gene expression coordinately regulated with NCAM1 during mouse kidney development.

HeatMap of gene expression in different renal compartments and time points during mouse kidney development and adulthood, that their expression was coordinately regulated with NCAM1 expression.

In mouse kidney development, the transcriptional factor PAX2 activates Wnt4 expression in vitro and in vivo, and also directly activates human WNT4 promoter activity [ 26].

During mouse kidney development expression of Cdh1/E-cad and Six2 was found to be almost mutually exclusive, with the exception of the cells that are going through the MET.

During mouse kidney development, ephrin-B2 is expressed initially in a subset of podocyte progenitors and subsequently in endothelial cells of the developing glomerulus, while expression of EphB4 was observed in endothelial cells of venous structures [ 94], suggesting the involvement of interaction between ephrin-B2 and EphB in glomerular microvascular assembly.

Of the TGFβ isoform null mouse lines, only Tgfb2 mutant mice exhibit defects in kidney development [6], [12], [13], [14].

In both mouse and possibly human kidney development tsh-family genes underlie the differentiation of ureteral smooth muscle (Caubit et al., 2008).

Targeted disruption of both Agtr1a and Agtr1b genes in mice resulted in abnormal kidney development characterized by tubular atrophy and interstitial expansion, papillary atrophy, and severe impairment of concentrating urine8,9.

FRAS1 has a role in renal development (32), and knockout mice have severely defective kidney development, along with syndactyly (33).

Although Cox-2 is generally associated with biologic events such as injury, inflammation, and proliferation [29], the knockout mouse model surprisingly shows abnormal kidney development.