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Two of the 13 genes were also concordantly regulated in the human tubulointerstitium and ROP- Os/+ mouse kidney (Table 5).
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Mice treated with intrarenal hAFSC after induction of ATN showed statistically significant comparisons, mostly at 7 and 14 days, in mouse cytokine levels, when compared with mice treated with either intrarenal vehicle saline solution (PBS) or just with ATN induction alone, or when compared with nu/nu mouse kidney before any treatment, as shown in Table S1 and Table S2 (Supplementary Data).
A primer complementary to the 5′-UTR of the MITF-A cDNA (R3, Table S3 of Supporting Information) and mouse kidney RNA were used for reverse transcription.
The list of genes differentially regulated in control and diseased human kidneys only showed significant enrichment for X and Y chromosomes (Table 4), while the differentially expressed genes in the mouse kidney showed enrichment not only for sex chromosomes but for various autosomes (including chromosome 4, 7, 14, 19) (Table 4).
In addition, the levels of cytokines in the hAFSC treated ATN mice, compared with basal nu/nu mouse kidney levels showed that there was an increase of anti-inflammatory cytokines such as IL-10 and IL-1Ra (Table S1).
Mouse kidney progenitor cell.
They are histologically regarded as a normal finding in the mouse kidney tissue.
Autoradiography was performed to qualitatively measure relative 64Cu intensity in mouse kidney sections.
A conceptual developmental framework has emerged for the mouse kidney.
M1 Fhit −/− and +/+ kidney cells were established in culture from whole mouse kidney.
g2 – Z. Gatalica, MG-U74Av2, mouse kidney tissue.
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