Sentence examples for mouse islets data from inspiring English sources
Also, the adenylate cyclase activator forskolin (10 µM) did not affect oxygen consumption in mouse islets (data not shown).
Similar results were observed in mouse islets (data not shown).
INS-1 cells express Tcf19 protein at a level that is similar to the mouse β-cell line MIN6, and both cell lines have moderately increased Tcf19 protein relative to mouse islets (data not shown).
In agreement with the immunofluorescence data from mouse islets, IGF-1R protein was present in β- but not α-cell lines (Figure 3C).
Application of the workflow for analysis of the mouse islet RNA-Seq data resulted in a splice junction database containing approximately 32,000 (B6) and 20,000 (CAST) splice junction polypeptides.
By contrast, we have previously detected Pask mRNA in mouse islets and MIN6 cells [ 18], data recently confirmed by others [ 20].
Our data also revealed that in mouse islets, Etv1 was strongly expressed in α-cells and Mlxipl was strongly expressed in β-cells.
In the pancreas samples of the Tg(RIP-luc) mice, luciferase-positive cells were only detected in islets (data not shown).
Similar results were obtained with 50 nmol/l wortmannin in MIN6 cells, pseudoislets and mouse islets, whereas 1 μmol/l wortmannin was required to obtain inhibition in human islets (data not shown).
In mouse islets hypoglycemia but not hyperglycemia increased the Bax/Bcl-2 ratio (p<0.01) (data not shown).
These data further suggest that those observed phenotypes in FGF21-KO mouse islets are due, at least in part, to the removal of FGF21 inhibition on islet GH signaling.
