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I'll keep this short, since the mouse is small.
Since the size of mouse is small, in order to get clear images showing details of the internal organization, we must choose thin slice (0.5 mm or less).
Two possible explanations for this are: (i) rod cone divergence in mouse is small (∼1; Tsukamoto et al., 2001); (ii) coupling might not be promoted when patching on rods.
Similar(57)
The cn/cn mouse is smaller than the cn/+being approximately two-thirds the size.
It should be noted that the body size of the homozygous mutant mouse was small in comparison to the control littermates (data not shown).
Although the EF121 mosaic mouse was smaller than the Q76 mice and exhibited a slightly ataxic phenotype with age, the mouse was able to continue to breed and sired 528 mice by 122 weeks of age.
At the end of the second week, the heart of TG mice is smaller than that of the WT littermates.
But mice are small and furry – how much can we extrapolate these findings to humans?
The lethality phenotype, however, cannot be explained by lack of Igf2, because although Igf2 +/−(P) and Igf2 −/− mice are small (50 62%), they are viable [70], [71], [73].
The global ablation of Fto expression in mice [14] results in high early mortality but the surviving mice are small, with reduced lean and fat mass.
KO mice were small, as LBM was 77% of normal.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com