Sentence examples for mouse intestinal mucosa from inspiring English sources

Salmonella effector AvrA dampened the proapoptotic innate immune response to Salmonella at the mouse intestinal mucosa [ 74].

(12) The expression of Wnt target genes is significantly increased in Runx3 −/− mouse intestinal mucosa without any alteration of the expression levels of TCF4 and β-catenin, and Runx3 + /− mice develop intestinal tumors.

Following oral administration of CTB-GFP expressing leaf material to mice, fluorescence microscopy and immunohistochemical analyses confirmed the presence of GFP in the mouse intestinal mucosa, liver and spleen while CTB remained in the intestinal cells [ 74].

This is supported by the enrichment of HNF4α IP DNA to the Cdx-2 promoter in the ChIP qPCR analysis of the mouse small intestinal mucosa (figure 5).

In order to further verify the HNF4α binding to the Cdx-2, trehalase, and cingulin promoters in vivo, ChIP analyses were performed on mouse small intestinal mucosa (figure 5).

This region was not analyzed in ChIP-chip, but we found a significant binding to the trehalase promoter in ChIP-chip analysis, which was verified by ChIP-qPCR in both Caco-2 cells and mouse small intestinal mucosa.

Notably, a very recent report has proposed that a significant number of the CD11clo cells found in mouse small intestinal mucosa, which fail to produce pro-inflammatory mediators in response to TLR ligation may be macrophage-like, based on the expression of F4/80 20.

Moreover, we observed that bacteria in the intestinal tract of ALF mice invaded the intestinal mucosa by pinocytosis at 9 h after GalN/LPS administration.

In accordance with the results of Peignon et al. [31] Hes-1 mRNA levels were found upregulated in intestinal tumors from Apc deficient mice compared to normal intestinal mucosa.

Therefore, we directly compared the intestinal mucosa of mice with CDC25 inactivation to mice treated with the topoisomerase I inhibitor irinotecan, which induces DNA damage thereby leading to cell cycle arrest [19].

Whereas the permeability to 4 kDa TD remained comparable between unchallenged Wt and Bcat mice, we noted increased leakiness of the intestinal mucosa of Bcat mice when challenged by limited exposure to the luminal irritant dextran sulfate sodium (DSS) for 16 h (Fig. 2F).