Sentence examples for mouse intestinal microbiota from inspiring English sources

We show that the mouse intestinal microbiota contains fungi and the cytokine responses towards this microbiota were significantly reduced in dectin-1 deficient macrophages.

For instance, disruption of the mouse intestinal microbiota decreases the LD50 for Salmonella from 10 cfu to less than 10 cfu. - Partial restoration of resistance to Salmonella is achieved by inoculating the disrupted mice with a fecal suspension from untreated mice.

This member of the angiopoietin-like family of proteins is selectively suppressed in the intestinal epithelium of normal mice by intestinal microbiota.

Previously published protocols for depleting mice of their intestinal microbiota by administering broad-spectrum antibiotics in drinking water were difficult to reproduce.

We attempted to deplete mice of their intestinal microbiota by providing ampicillin, vancomycin, neomycin, and metronidazol ad libitum in drinking water according to the previously published protocol[20].

In the AAD mice model, the intestinal microbiota was almost eliminated as only few bands in the DGGE profiles, and the tissue architecture of the colon was damaged dramatically.

60 61 Transient perturbation of the microbiota with antimicrobials alters brain-derived neurotrophic factor expression, exploratory behaviour and colonisation of germ-free mice suggesting that intestinal microbiota impact is not limited to the gut and the immune system, but may involve the central nervous system.

To confirm that bacterial spread was responsible for the high mortality observed in Casp8ΔIEC mice, we severely reduced the intestinal microbiota by treating Casp8ΔIEC mice with a combination of different antibiotics prior to administration of the stimulus poly(I C).

In conclusion, we present a generally accessible protocol for depleting mice of their cultivable intestinal microbiota by administering an antibiotic concoction by gavage every 12 hours.

We present a robust protocol for depleting conventionally raised mice of their cultivatable intestinal microbiota with antibiotics by gavage and show that the biological effect of this depletion phenocopies physiological characteristics of germ-free mice.

Clearly, these differences relate to the ease of C. jejuni to establish a niche in germ free mice whereas the complex intestinal microbiota present in SPF conditions severely restrain C. jejuni expansion/colonization.