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Bjerknes, M. & Cheng, H. Clonal analysis of mouse intestinal epithelial progenitors.
Vidal, K., Grosjean, I., evillard, J. P., Gespach, C. & Kaiserlian, D. Immortalization of mouse intestinal epithelial cells by the SV40-large T gene.
The nematode vesicles are internalized by mouse intestinal epithelial cells in vitro and suppress genes involved in inflammation and immunity, including the receptor for the alarmin IL-33 and a key regulator of mitogen-activated protein kinase (MAPK) signalling, DUSP1.
In vivo studies further revealed that JNK2 deficiency led to upregulation of β-catenin and increase of GSK3-β phosphorylation in JNK2-/ mouse intestinal epithelial cells.
Recently a differential role of IL-10 as an anti-apoptotic mediator protecting the mouse intestinal epithelial cells from IFN-γ or TNF-α mediated apoptosis by diminishing the Fas expression has been shown [29].
Y2+3 has demonstrated comparable anti-inflammatory effects in IL-1-stimulated mouse intestinal epithelial Mode-K cells.
Similar(46)
Therefore, we proposed that loss of E-cadherin from the developing mouse intestinal epithelium would disrupt intestinal epithelial morphogenesis and function.
We hypothesized that rhythmicity of PER2 would diminish in amplitude along a continuum from mouse small intestinal explants, intestinal organoids, a nontransformed mouse small intestinal epithelial (MSIE) cell line (Whitehead et al., 1993) and transformed human colorectal adenocarcinoma cells (Caco-2).
To determine whether the nematode-derived exosomes can enter mammalian cells, uptake was examined in mouse small intestinal epithelial cells, a cell type that is naturally in direct contact with H. polygrus in vivo.
A mouse Hnf4α intestinal epithelial conditional knockout colony was generated exactly as described recently [11].
We hypothesized that rhythmicity of a key circadian component, PERIOD2 (PER2), would diminish along a continuum from ex vivo intestinal organoids (epithelial 'miniguts'), nontransformed mouse small intestinal epithelial (MSIE) cells and transformed human colorectal adenocarcinoma (Caco-2) cells.
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