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This is in accordance with recent observations that F1C fimbriae contributed to E. coli persistence in an infant mouse intestinal colonisation and biofilm formation model [ 35].
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Two weeks after the end of the WIRS, we took the same parts of faecal samples for bacterial genome extraction and detected the Blab/c mice intestinal flora colonisation using Miseq methods.
26 Disturbance of intestinal microbiota composition resulting from chronic intestinal colonisation with pathogens or overgrowth of commensal bacteria in the small intestine 19 27 28 29 may lead to disruption of these functions.
K99 fimbriae are important for intestinal colonisation by bovine strains of enterotoxigenic Escherichia coli.
Confocal microscopy revealed that LSs can translocate into mouse intestinal wall.
Therefore, we proposed that loss of E-cadherin from the developing mouse intestinal epithelium would disrupt intestinal epithelial morphogenesis and function.
Although acute EPEC infection is known to cause diarrhoea, the effects of chronic low-level intestinal colonisation are unknown.
Some acids may also prevent intestinal colonisation of Salmonella in animals [ 5].
The time-point of the intestinal colonisation by these organisms during the nursing period is unknown.
Clayton et al. [ 16] observed that mutations in Salmonella enterica fimbrial subunits genes led to reduced intestinal colonisation in chickens.
Oostdijk's group demonstrated a statistically significant increase in intestinal colonisation with Gram-negative bacteria resistant to ceftazidime, tobramycin or ciprofloxacin (P <0.05) [ 44].
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