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Moreover, AM9D could also be detected in adjacent, non-injected mammary tumors of the same mouse, indicating a wider distribution pattern than might be expected from intratumoral injection.
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The finding of no expression of PWS region sno-lncRNAs in mouse indicates a possible limitation of the use of mouse models to study human PWS.
Six cycles of O/R reduced infarct size 24 h later in WT mice, indicating a late PC effect.
The biocompatibility was examined in mice indicating a good tolerance upon subcutaneous implantation with only a mild inflammatory response.
In addition, the incidence of metastasis was also increased in ATM−/− Gadd45a−/− mice, indicating a role of Gadd45a in the prognosis of hematopoietic malignancies.
Immunization with PLP91 110 led to more severe EAE in DR3.CD8−/− mice compared to HLA-DR3 mice indicating a regulatory role for CD8 T cells.
Another group reported a delayed response to sleep deprivation and altered sleep cycles in REV-ERBα null mice, indicating a role of REV-ERBα in sleep.
The plasma concentration profile in mice with glycerol‐induced acute renal failure was similar to that in normal mice, indicating a minimal contribution of kidney to systemic clearance of HGF.
However, local SKF-81297 (selective DA D1-R agonist) in dorsal striatum reduced DA release equally in both control and Tg mice indicating a comparable function of DA D1-R in the direct striato-nigral pathway.
DOX cardiotoxicity is reproduced in several species including mice, indicating a non-species specific mechanism of toxicity [3].
Mice transplanted with LSK-EVAi cells showed a smaller thymus compared with the LSK-CT-injected mice, indicating a less efficient thymic reconstitution (Fig. 3A, left panel).
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