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A study performed in mouse indicates that retinoblastoma arise from a precursor cell that is naturally death-resistant [34].
Data from our ILC3-specific conditional Gata3 knockout mouse indicates that GATA-3 acts upstream of T-bet to direct NCR+ ILC3 development from a CCR6−T-bet− precursor (Zhong et al., 2016).
Previous work using the Per1-GFP mouse indicates that phase heterogeneity persists after acute release into DD, but that the phase distribution of SCN oscillators is affected [18].
The observed decrease in the diaphragm, which is the most severely affected of the muscles in the mdx mouse, indicates that tranilast was able to reduce fibrotic accumulation.
Nonetheless, the lack of conservation of the IGF2R intron 11 DMR in the human, dog and mouse indicates that DMRs are not always conserved between eutherians and metatherians.
Moreover, evidence from the Wnt5a knockout mouse indicates that normal morphological development of OB interneurons is disrupted in the absence of endogenous Wnt5a.
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Anoikis was suppressed in the non-adherent culture of hepatocytes isolated from gld/gld mouse, indicating that Fas signal induces hepatocyte anoikis.
Recent studies using conditional knockout mice indicate that Notch1 as well as Notch2 plays an important role postnatally in liver development and in maintenance of hepatic function.
Transepithelial resistance was not altered in Tg and Ko mice, indicating that tight junctions were not affected.
A similar distribution was observed in K5cre-CMVcaNrf2 mindicatingathat tighttight junction permeability is not grossly affected (Fig 5B).
Our data derived from biodistribution experiments in the Rip1Tag2 mouse indicate that at least in the presented experimental model, there is no such window.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com