Sentence examples for mouse including the from inspiring English sources
Indeed, Regeneron's formula appears to be paying off every drug put into clinical trials in the last five years has been a monoclonal antibody from the VelocImmune mouse, including the LDL cholesterol-lowering drug that spent less than two years in preclinical development.
Therefore, we also generated a transgenic mouse carrying the MSCV-EGFP cassette using lentiviral-mediated gene delivery to two-cell-stage embryos and performed detailed analyses of this mouse, including the pattern of EGFP expression in skeletal muscles.
We then irradiated one hind leg of each mouse including the tumor area (5 Gy, 2 times at 72 h intervals) at 12 days after the tumor cell inoculation and the other hind leg including the tumor area was used as the mock-irradiation control.
Tissue-specific Cre transgenes have been generated for nearly every tissue in the mouse, including the bladder urothelium.
Accumulation of Gb3 has been documented previously in several tissues of α-Gal A-deficient mouse including the brain [ 19, 20].
To investigate the presence of the Smc5/6 complex in the testis, we performed western blot analysis for Smc6 on several organs of the mouse, including the testis.
Almost all bones of the mutant mice, including the calvariae, vertebrae, tibiae, femurs, ribs, limbs and sternums were defective.
A pharmacokinetic model was developed to assess the disposition of the coencapsulated drugs in mice, including the free and encapsulated fractions after measurement of the total plasma concentrations.
The selective inhibition of bacterial β-glucuronidases was recently shown to alleviate drug-induced gastrointestinal toxicity in mice, including the damage caused by the widely used anticancer drug irinotecan.
A subanalysis examining the interlimb difference showed that the response to loading in young Sost KO animals was significantly greater than in LC mice, including the relative MS/BSday0 15, nearly all relative day 15 static microCT parameters (rCt.Ar, rCt.Ar/T.Ar, rCt.Th, rCt.vTMD), all relative periosteal histomorphometric parameters, but none of the relative endocortical bone formation indices.
Regulatory B cells control inflammation and autoimmunity in mice, including the recently identified IL-10-competent B10 cell subset that represents 1% to 3% of spleen B cells.
