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Because of the paucity of information on the network patterns of the mouse hippocampus, we investigated the electrical patterns in the behaving animal using multisite silicon probes and wire tetrodes.
Using ex vivo slice preparations derived from the CA1 region of the mouse hippocampus, we first assessed the impact of METH on synaptic plasticity.
To examine the localization of p75NTR in fibers in the mouse hippocampus, we utilized immuno-EM.
To assess a potential role of xCT in the mouse hippocampus, we performed fear conditioning and passive avoidance for long-term memories and examined hippocampal synaptic plasticity in wild-type mice and xCT-null mutants, sut mice.
To uncover neurobiological and cellular processes that were significantly altered in Glud1 mouse hippocampus, we first carried out Gene Ontology (GO) analyses on the up- or down-regulated genes identified above.
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To characterize gene expression changes in the mouse hippocampus due to circadian time, we compared genome-wide gene expression among our three control time-points (CC40', CC4 and CC12).
We used mouse hippocampus weight data from 35 BXD lines plus the parental C57BL/6 J and DBA/2 J strains, adjusted for age, sex, body weight, and brain weight minus hippocampus weight [ 4, 30] (GN13031).
The high expression of Jarid1c that we found in the mouse hippocampus is consistent with the cognitive defects in human patients with JARID1C mutations [1], [2].
Here, we report that the iv mouse hippocampus exhibits right isomerism of the synaptic distribution of the ε2 subunit.
In this study, we discover that the iv mouse hippocampus also contains two separable populations of synapses on apical and basal dendrites of CA1 pyramidal neurons.
Thus, we conclude that the iv mouse hippocampus exhibits right isomerism with regard to the synaptic distribution of the ε2 subunit.
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