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The main challenge when imaging the mouse hearts is to achieve spatial resolution and noise levels that permit resolving the millimetre-thick murine myocardial wall.
Finally, transgene-driven overexpression in mouse hearts is known to induce an unfolded protein response which can reverse the expected phenotype.
Ly6-G+ cell counts to determine neutrophil density in control and STZ-treated WT and EphA2-R-M mouse hearts is shown in Figure 4.
Surprisingly, we show here that the impaired mitochondrial respiration and reduced ATP production observed in Lrpprc conditional knockout mouse hearts is caused by an ATP synthase deficiency.
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Results from cardiac action potential mapping with intact mouse hearts are provided.
The results showed that when mouse hearts were subjected to ex vivo I/R, Tg mice have a higher CK and LDH, a larger myocardial infarct size and lower heart function recovery.
Although p38 was about 17-fold more active in TG than non-transgenic (NTG) mouse hearts, TG mouse hearts were morphologically and functionally similar to those of NTG littermates.
It was postulated that the mechanism of synergism and reduced cytokine toxicity was related to anti-CD2-induced alterations in anti-CD3-induced T-cell activation.C57BL/6 (H-2b) mouse hearts were transplanted to CBA (H-2k) mice.
While mouse hearts are thin and tiny, pig hearts are a closer match for ours, and will reveal if the Srivastava's reprogramming trick works at a human scale.
Rat and mouse hearts were harvested immediately after sacrifice and snap frozen in liquid nitrogen.
Isolated adult mouse hearts were diced into small tissue pieces less than 1 mm3 in size.
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