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Results from cardiac action potential mapping with intact mouse hearts are provided.
While mouse hearts are thin and tiny, pig hearts are a closer match for ours, and will reveal if the Srivastava's reprogramming trick works at a human scale.
The functional properties of mid-foetal mouse hearts are as yet quite elusive.
Moreover, the triggered inflammation increased cardiomyocyte proliferation, which is considered to be an efficient regenerative response once neonatal mouse hearts are injured.
The vast majority of both GFP+ and Mrc1+ cells were CD45+ and CD11b+, indicating that GFP+ and Mrc1+ cells within Cx 3cr1 GFP/+ mouse hearts are predominantly myeloid leukocytes.
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The results showed that when mouse hearts were subjected to ex vivo I/R, Tg mice have a higher CK and LDH, a larger myocardial infarct size and lower heart function recovery.
The main challenge when imaging the mouse hearts is to achieve spatial resolution and noise levels that permit resolving the millimetre-thick murine myocardial wall.
Although p38 was about 17-fold more active in TG than non-transgenic (NTG) mouse hearts, TG mouse hearts were morphologically and functionally similar to those of NTG littermates.
It was postulated that the mechanism of synergism and reduced cytokine toxicity was related to anti-CD2-induced alterations in anti-CD3-induced T-cell activation.C57BL/6 (H-2b) mouse hearts were transplanted to CBA (H-2k) mice.
Rat and mouse hearts were harvested immediately after sacrifice and snap frozen in liquid nitrogen.
Isolated adult mouse hearts were diced into small tissue pieces less than 1 mm3 in size.
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