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Haematoxylin-eosin staining and transmission electron micrographs showed focal distortion of myofibers in the Mecr transgenic mouse hearts, accompanied by aggregation and an unusual ultrastructure of the mitochondria.
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His work there was mostly entering and analyzing computer data on the function of mouse hearts.
Last year Wagers showed that GDF11 reversed some effects of ageing in mouse hearts.
Thymosin b4 injection increases fibroblast proliferation in mouse hearts following myocardial infarction (Qian et al., 2012).
In addition, the RCAN1.4 protein was easily detected in embryonic mouse hearts at E10.5 but not in embryonic mouse heads at E10.5, while RCAN1.1 protein levels were similar between embryonic mouse hearts and heads (Figs. 1B and S1A).
LAD-ligated mouse hearts were compared against sham-operated mice samples and also against non-manipulated P10 mouse hearts.
An example is 'Heart' and 'Malign tumör i hjärtat' (literally 'Malignant neoplasm of heart') accompanying the ICD-10 code C38.0.
Previous work has shown that progressing lipid accumulation and myocardial fibrosis in hearts of ATGL-deficient mice was accompanied by LV hypertrophy and impaired LV systolic function in vivo (Haemmerle et al., 2006).
Transgenic expression of DN-Lats2 was used to inhibit endogenous Lats2 in the mouse heart.
Figure 1 Mouse heart MR (left) and fused with 18F-FDG static PET (right).
Meanwhile, T0901317 treatment improved mice survival, accompanied by significant ameliorations of myocardial injury and dysfunction in wild-type mice but not in SIRT1-/ mice.
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