Sentence examples for mouse heart we from inspiring English sources

Using EC isolated from mouse heart, we show that endogenous ROS increased eNOS activation and nitric oxide (NO) synthesis through activation of the survival kinase AMPK.

To characterize the effect of short-term pacing-induced dyssynchrony on gap junction distribution in the mouse heart, we paced mice for 6 hours (3 4 half-lives of Cx43) [ 24- 26] and assessed Cx43 localization using immunofluorescence staining.

To identify Wnt signaling in the adult mouse heart, we used the Axin2-LacZ reporter mouse which will result in LacZ expression in those cells that have active canonical Wnt signaling.

To determine whether the induced inflammation increased the number of newly formed cardiomyocytes in the neonatal mouse heart, we performed pulse-chase labeling of 5-bromo-2-deoxyuridine (Brdu) over a 21-day period after ZA microinjection of neonatal 1-day-old mice.

Since we observed these cells in the subepicardium of 13 dpc mouse hearts, we can hypothesize for the first time on the existence of hematopoietic potential in the subepicardial cells.

To determine whether GFP or Mrc1 expression predominantly marks myeloid leukocytes in Cx 3cr1 GFP/+ mouse hearts, we gated viable cells (viability dye−) and determined GFP or Mrc1 expression relative to CD45 or CD11b expression (Supplemental Fig. 1.

This included an assembly of mouse heart reads because we could compare those against the reference genome that is available.

To evaluate the efficiency of exon skipping in the mouse heart in vivo, we used AAV serotype 9 (AAV9), which has been shown to have a high cardiotropism in mice (Inagaki et al, 2006).

But more importantly, the classes of proteins identified and enriched in our dataset mirror those found in a recently published comprehensive mouse heart proteome [33], which we used as a benchmark.

Inspired by the important finding of the transient regenerative potential in the neonatal mouse heart (Porrello et al., 2011), we established a mouse culture system of P1 neonatal CMs cultured on 2 MPa, 20 kPa, and 5 kPa substrates.

So, the Sca-1+ cells we isolated from mouse heart tissue should be identified as CPCs.