Sentence examples for mouse heart failure from inspiring English sources

In contrast, in the TG9 mouse heart failure is a primary effect of a cardiac-specific transgene.

The transcriptional mechanisms underlying this bidirectional control of β2-subunit expression, however, remain to be elucidated in the context of changes in β1 and β3 subunit expression in human and old tg CaV1.2 mouse heart failure.

The usefulness of STE in identifying segmental LV dysfunction in mouse heart failure model has been demonstrated previously using a conventional clinical echocardiography system [ 13] and a high-resolution rodent ultrasound system [ 14].

The load-dependent regulation of SERCA and BNP was analysed in the MLP-KO-mouse heart failure model.

In contrast to the normotensive HCM mouse, many heart failure models are generated by inducing or mimicking a hypertensive or pressure-overloaded state.

Rnd3+/− mice were viable; however, the mice developed heart failure after pressure overload by transverse aortic constriction (TAC).

Liver weights were not increased in mice with heart failure compared with normal mice, and so, despite severe LV failure, there is no liver congestion.

However, these mice developed heart failure with apoptotic cardiomyopathy after the mice were exposed to pressure overload.

GATA4-haploinsufficient mice were more susceptible to imatinib cardiotoxicity with significantly increased incidence (reaching almost 100% of treated older mice) of heart failure and dilated cardiomyopathy.

Physiologist Andrew Marks of Columbia University and colleagues previously reported that, in mice with heart failure, calstabin doesn't bind to the channels as it should.

Rnd3 haploinsufficient mice develop heart failure along with elevated Rho kinase activity after pressure overload.