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Again, surprisingly, mouse heart cells enlarged as they would in a well-conditioned athlete.
Force's team then showed that Gleevec caused mouse hearts and cultured mouse heart cells to develop similar abnormalities.
The authors present data indicating that newt and zebrafish heart muscle cells contain centrosomes, whereas adult mouse heart cells do not.
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Because the parameter space of the mouse heart cell model has been less extensively explored than that of the mammalian circadian clock, we designed for screening rather than optimisation here.
Mouse heart endothelial cells (MHEC) were prepared from collagenase treated myocardial tissue, using a two step positive selection protocol with anti-CD31 and anti-ICAM-2 coated magnetic beads, as described [25].
Primary mouse heart endothelial cells were obtained from the Center for Vascular Biology Research at Beth Israel Deaconess Medical Center.
In order to examine the effects of Nox2 overexpression in ECs, mouse heart endothelial cells (MHEC) were isolated from two independent binary transgenic mouse lines as described [ 10].
In another investigation, 99mTc-losartan was used for noninvasive imaging of angiotensin receptors in mouse heart muscle cells after permanent ligation of the left anterior descending artery [ 94].
Efsevin can also correct irregular heart rhythms in human and mouse heart muscle cells, therefore the new role for mitochondria in controlling heart rhythms found by Shimizu et al. appears to be shared in other animals.
The control tissues used were: term placenta (activin βA, βB, GDF11, TGFβ1, -2, -3); pregnant mouse endometrium (BMP2); mature rat ovary (BMP4, GDF5); cycling mouse endometrium (BMP7); mouse heart (GDF8); JEG3 cells (Nodal).
Primary mouse heart endothelial cells (MHECs) were treated with conditioned medium (CM) harvested from ASC-Ns, ASC-Rs or ASC-Ls and examined for proliferation, wound healing and tube formation.
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