A previous study using mdx mice had reported that gains in muscle mass due to loss of myostatin activity were maintained as the mice aged (21).
In a similar manner, experiments using neurons cultured from transgenic AD mice have reported that intraneuronal Aβ increases the vulnerability of neurons to stressful cellular environments such as excitotoxicity and oxidative stress [11].
Previous amyloid PET studies in AD transgenic mice have reported various findings [ 27].
However, while Aire−/− mice have reported defects in Foxp3+ T-cell development 43, 64, Ltbr−/− mice do not 65, 66.
While the literature on purinergic responses is varied, some authors using ATP in ApoE−/− mice have reported relaxation [10].
Additionally, studies with CnA transgenic mice have reported an increase of oxidative fibers in the skeletal muscle [ 8, 9].
Studies of Per3− / − mice have reported none or only subtle behavioural changes in circadian properties [ 3, 4, 16– 16].
Studies in mice have reported that subchronic or chronic phthalate exposure leads to increased serum and/or liver tri glycerides (Mapuskar et al. 2007; Pereira et al. 2006).
A number of studies in humans and mice have reported the presence of inflammatory neutrophils and macrophages in the uterus, decidua, cervix and fetal membranes during labor.
Previous studies of disseminated C. albicans infection, utilizing IL-17A−/− and IL-17RA−/− mice, have reported that Th17-cell responses are beneficial to the host 6.
