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A paper published this week in Science presents a new picture of how taste is encoded in the mouse gustatory cortex, the region of the brain devoted to processing taste stimuli.
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In mice, taste receptor cells synapse onto primary afferent fibers, and the signals are relayed to the gustatory cortex via the nucleus of the solitary tract, parabrachial nucleus, and thalamic gustatory area, with a concentration of sweet-activated neurons in the rostral fields of these regions [ 96].
The gustatory cortex is reciprocally connected with the aforementioned basal forebrain, thalamic, and pontine nuclei.
The responsiveness of neurons in the insular gustatory cortex of the macaque monkey is independent of hunger.
Finally, the hypothesis of frontal operculum as primary gustatory cortex and lateral prefrontal cortex as secondary was also supported by the results from dynamic causal modeling.
Neuroscientists have known for a while that odor receptors in the nose send signals to the the brain's taste center, also known as the gustatory cortex.
Katz, DB; Simon, SA; Nicolelis, MAL, Taste-specific neuronal ensembles in the gustatory cortex of awake rats., The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, vol 22 no. 5 (2002), pp. 1850-1857 [10.1523/jneurosci.22-05-01850.2002] [abs].
Similar "timing chaos with serial order" has been observed in vivo in the gustatory cortex [23].
Each of these modalities remains quite separate from the others and these divisions can be followed in the upper sensory centers, up to the gustatory cortex [6].
Since this form of memory is known to be dependent on a number of brain structures, including gustatory cortex and amygdala [24], [25], [26], these results attest to the specificity of the remote memory deficits of these two mutant strains.
It was later shown that PKMζ activity in the hippocampus, gustatory cortex, and basolateral amygdala is necessary for several forms of specific and accurately learned memories, but PKMζ has not yet been proven necessary for procedural memories [5], [7].
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