Sentence examples for mouse growth we from inspiring English sources

To determine whether introduction of the Cre gene in the Ins1 locus would cause any deregulation of glucose homeostasis or impact mouse growth, we generated cohorts of male and female C57Bl/6J heterozygous Ins1Cre and littermate controls and followed them for 24 weeks.

To obtain further insight into the 21 rescued mouse growth phenotypes, we retrieved information for known enzymopathies associated with the genes by mapping a recently assembled compendium of human inborn errors of metabolism (IEMs) onto the mouse model.

We considered three scenarios: at optimal mouse growth rate (diamonds in Fig. 1D), at optimal B. thetaiotaomicron growth rate (triangles in Fig. 1D), and during nutrient competition (squares in Fig. 1D).

We show that overexpression of Wnt4 in the mouse growth plate may also influence chondrocyte maturation, as shown by reduced zones of proliferating chondrocytes and expanded zones of Col10a1 hybridization and hypertrophic chondrocytes in R26floxneoWnt4; Col2a1-Cre mutants.

We here present the first report of rhGALNS biodistribution specifically in the mouse growth plate and articular cartilage, indicating that non-tagged rhGALNS successfully diffuses through the avascular cartilage to reach chondrocytes, the primary target cells.

We therefore constrained human hepatocyte growth rate to the average of rat and mouse growth rates (G = 6.6x10−4 mass equivalent doublings/min) (Additional file 13: Table S1) and changed only the metabolic demand parameter to fit human regeneration data.

The mean tumor volume and mouse weight were used to construct the curves of tumor growth versus mouse growth to evaluate therapeutic efficiency and toxicity.

For example, genetic disruption of mouse growth hormone signalling, which decreases insulin growth factor (IGF) synthesis, delays puberty [28].

For the growth data, a mixed model with repeat approach was fitted to estimate genotype effect on mouse growth.

They grew well in media containing human growth factors or mouse growth factors, supporting the hypothesis that the cells contain only human DNA (Table 1).

To determine whether tankyrase 1 might mediate similar functions in mouse growth, the body weight of 8 to 9 week-old WT and TANK1−/− mice was measured.