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Mice infected with 103 parasites presented a peak parasitemia lower (P<0.05) than the mouse group infected with 104 but not with 105 parasites.
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In repeated experiments, mice infected with 102 parasites presented a peak parasitemia lower than mouse groups infected with 104 or 105 (P<0.01 in both cases).
All mice infected with wild type bacteria succumbed to infection, whereas all mice in the group infected with the ΔM5 mutant survived (Figure 3A).
In a particularly revealing experiment, the Romesberg group infected mice with either wild-type Escherichia coli or E. coli harboring a noncleavable mutant of LexA.
Separate sets of mice were maintained for each experimental group infected with clade 1.0 for determination of viral titers and histopathology experiments.
For example, in order to compare the response to Qs and BALB/c mice, data from all Qs groups (infected with either N. caninum type and the two different time points) were considered as "Qs".
The survival rates of mice (n = 12) were similar for groups infected with wild-type or single etrx mutants, although there was a moderate but not significant attenuation for the double mutant D39 luxΔ etrx1Δ etrx2 (Fig 6G).
At 10 cfu/mouse, survival dropped to 0 and 23% in the groups infected with FP28 and FP262, respectively.
Seven groups of animals were studied including control group (mice not infected with A. fumigatus).
C57BL6 mice (8 weeks female, 5 mice per group) were infected with PAO1 intranasally, and broncho-alveolar lavage (BAL) was performed 18 h post infection.
Six mice per group were infected by injecting a single dose of 5 × 10 infectious viral particles via the tail vein.
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