Sentence examples for mouse germ line from inspiring English sources

Both homoplasmic and heteroplasmic mice have been produced, allowing modeling of mtDNA transmission through the mouse germ line.

Silver nanoparticles also proved to be toxic to in vitro mouse germ line stem cells as they impaired mitochondrial function and caused leakage through the cell membranes.

Much of the advancement in mouse models for cancer during the past 2 decades can be attributed to our increasing capacity to specifically modify the mouse germ line.

Besides, silver nanoparticles can also induce toxicity to in vitro mouse germ line stem cells by impairing mitochondrial activities and cause leakage through the cell membranes by changing its permeability to sodium and potassium ions.

In chimeras with intact embryos, mouse ES cells contribute to a wide range of adult tissues, including germ cells, providing a powerful approach for introducing specific genetic changes into the mouse germ line (3).

This suggests strong purifying selection against deleterious mtDNA mutations in the mouse germ line.

(D2) Generation of several new mouse strains (at the same time): Among the different technical approaches available (transgenesis, retroviral introduction of mice or human hematopoietic cells, or injection of human leukemic cells into mice), germ-line transgenesis is preferred, as the generated mice strains can be shared.

However, only Dazap1 was expressed in a mouse germ cell line GCl-spg [ 19] and a Sertoli cell line MT4.

However, in mouse embryos germ line restriction is induced in transcriptionally active cells by expression of the transcription factor Blimp1 (PrdMouseMouse Genome Informatics), which inhibits mesoderm specification in nascent PGCs through repression of a specific set of genes (Ohinata et al., 2005).

It has also been described that TU-1A is regulated by an alternative promoter sequence [6], [8] that proved to be very active when transfected in the GC2 mouse germ cell line [7].

The high frequency of InsG in longer runs of guanines observed in our study suggests that such sequence domains may be particularly sensitive to insertions in the mouse male germ line.