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In an attempt to understand and identify the molecular mechanism/s of domestication we have examined the number of such genes in the human and mouse genomes and analysed the features of their genomic insertions sites.
We conducted a comprehensive genomic analysis of glycolytic enzymes in the human and mouse genomes and identified several intronless copies for all enzymes in the pathway, except Pfk.
Using a test that compares mutations on the human and mouse genomes, and that takes into account those which cause changes in a protein, the authors of the analysis found that some 5percentt of each genome is under selective pressure.
Most data concerning LINE-1 biology and evolution are derived from the human and mouse genomes and are often assumed to hold for all placentals.
Most of the current data concerning LINE-1 biology and evolution result from investigations of the human and mouse genomes and are often assumed to hold for all eutherians [1].
Taking the cell cycle as an example, we examined 356 genes of this pathway that are orthologous between human and mouse genomes and expressed in ESCs and EBs (Table S1).
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Zhang, Y. et al. Spatial organization of the mouse genome and its role in recurrent chromosomal translocations.
The consortium, however, is also working on the mouse genome and intends to put that and other important tools for interpreting the human genome in the public domain.
Celera's president, Dr. J. Craig Venter, said that he would draw the DNA from three strains of mouse, to study the natural variation of the mouse genome, and that he would assemble a "humanized mouse genome," one with the genes arranged in the same order as their counterparts on the human genome instead of in the natural mouse order.
Here, we screened the mouse genome, and found that tryptophan hydroxylase (TPH) is implicated in the maturation of sensorimotor gating.
Using genetic engineering, researchers incorporate a gene that codes for the protein into the mouse genome and fuse the glowing protein with synaptic molecules.
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