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In particular, we aimed to make a comprehensive comparison of genetic variation in all of the 300 000 ENCODE genomic features by integrating these elements with the mouse genome sequences.
Comparative sequence similarity search to human and mouse genome sequences revealed that 11% of the isolated ETS displayed high similarity to genomic sequences located on the syntenic chromosomes HSA4 and MMU5 of the human and mouse reference genome assemblies pointing to highly conserved genome regions in these species.
Just as comparing the human and mouse genome sequences provides important clues about gene function, so, too, does comparing the DNA sequence among people.
Similarly, private companies announced that they have rough copies of the rice and mouse genome sequences (ScienceNOW, 27 April).
Mouse genome sequences (February 2006 assembly) were downloaded from ftp://hgdownload.cse.ucsc.edu/goldenPath/mm8/chromosomes/.
In this work, the mouse genome sequences from UCSC (mm9) have been used for splicing event identification.
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It was estimated that the M. musculus B6 strain, for which the whole-genome sequences are available, has about 60 copies of an Sp100-rs gene, but this genomic portion is unassembled (Mouse Genome Sequencing Consortium 2002).
Genomic sequences were also retrieved from the mouse genome sequence as reported in the NCBI 37 July 2007 assembly (UCSC Genome Browser).
Genomic coordinates of extended human gene loci were transferred to the mouse genome sequence using the UCSC Lift Genome Annotations tool (http://genome.ucsc.edu/cgi-bin/hgLiftOver).
The Mouse Genome Sequencing Consortium undertook the multimillion dollar task of decoding the 2,500 million units of DNA in the mouse genome.
By the 1700's, mouse fanciers in Japan and China had domesticated many varieties of mice, mostly from musculus and domesticus, and Europeans later imported them, according to an article last week in Nature by the Mouse Genome Sequencing Consortium.
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