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He added that he was switching his 300 sequencing machines to analysis of the mouse genome, knowledge of which will help researchers interpret what human genes do.
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A caveat to the current work is that maps of genetic variation in the mouse genome are incomplete, a knowledge gap that promises to be filled by more informative SNP arrays [ 47] and next-generation sequencing [ 48, 49].
The mouse is an increasingly used preferred model in preclinical CA studies due to the knowledge concerning the mouse genome and the general availability of genetically modified mice.
But the consortium directors' news release neglects to mention that their rival, Dr. J. Craig Venter, the former president of Celera Genomics, decoded the mouse genome more than a year ago.
Based on this knowledge and avoiding sequences repeated in the mouse genome, we constructed an Oct4-specific LATE-PCR assay taking advantage of the flexibility that this technique affords for primer design [ 8].
The mouse genome has been decoded separately by both the international consortium and the Celera Genomics Corporation of Rockville, Md., the same rivals who vied in decoding the human genome.
Biologists believe the mouse genome will be essential to interpreting the human genome.
It is clear that the mouse genome is likely to emerge as a vital guide for interpreting the human genome.
The Mouse Genome Sequencing Consortium undertook the multimillion dollar task of decoding the 2,500 million units of DNA in the mouse genome.
All but 300 of them have a functional counterpart in the mouse genome.
Celera said its mouse genome would be available only to subscribers to its database.
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