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The consortium of scientists that examined the mouse genome found 25 cases in which humans have a single gene and the mouse a cluster of related genes.
Recently, a study of gene duplicates in the mouse genome found that relocated gene copies following duplication, and in particular retrotransposed copies, evolved faster than paralogs in their ancestral location [ 16].
There were 51 sliding windows of the mouse genome found to have Z>1, indicative of higher microsynteny conservation, and 91 intervals found to have Z<-1, indicative of lower microsynteny conservation.
TF-target gene links found in the matching step were retained only if the PWM match with the human promoter region, as well as with the promoter of the orthologous gene in the mouse genome (found in the HomoloGene database [ 50]), were above the default cutoff.
A previous study that analyzed the structure of MMERVK10C elements in the mouse genome found that the majority of these elements have 3′ deletions removing the start of the gag open reading frame as well as the major part of env (Reichmann et al., 2012).
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to the presence of a Xiap-like sequence found on mouse chromosome 7 during sequencing of the mouse genome (see: http://apr2006.archive.ensembl.org/Mus_musculus/domainview?domainentry=IPR001370).
Here, we screened the mouse genome, and found that tryptophan hydroxylase (TPH) is implicated in the maturation of sensorimotor gating.
We re-aligned the >24,600 Illumina probes to the mouse genome and found that 20,328 probes are of high mapping quality.
Surprisingly, in the mouse genome, we found a very low percentage of TPAs, in comparison to the human genome (<2%) (P << 0.001 for the likelihood of the number in mouse, given the human percentage as an expectation, using binomial statistics).
Using this model, MacBeath and coworkers screened 31,302 peptide sequences corresponding to the C-termini of all translated open reading frames in the mouse genome and found no less than 18,149 PDZ-peptide interactions.
We also identified two similar tripartite chimeric retroelements in the mouse genome and found that WEIRD, the major component of fungal bipartite chimeric retroelements, is a non-coding sequence highly expressed in various M. grisea tissues and during plant infection.
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CEO of Professional Science Editing for Scientists @ prosciediting.com