Sentence examples for mouse genetics we from inspiring English sources

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Furthermore, using mouse genetics, we showed that CR cell density severely affects the architecture of layer 1, a key site of input integration for neocortical networks, leading to an excitation/inhibition ratio imbalance.

By using mouse genetics we provide here the final proof that Mad2 is essential for correct chromosome segregation during normal first meiotic cell divisions in mouse oocytes, and not only upon treatment with spindle inhibitors such as nocodazole.

By combining region-specific isolation of astrocytes followed by transcriptome analysis, two-photon excitation microscopy, and mouse genetics, we identified the thyroid hormone transporter OATP1C1 as the SR101-uptake transporter in hippocampus and cortex.

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As the boom in mouse genetics continues we can expect the generation of many more genetic models that will continue to aid in the advancement of our understanding of the BBB.

Inbred strains are a distinctive feature of mouse genetics and we discuss their history, advantages and disadvantages.

Using an in vivo reporter of Shh signaling, mouse genetics, and systems modeling, we show that a spatially and temporally changing gradient of Shh signaling is interpreted by the regulatory logic of a downstream transcriptional network.

Here we use mouse genetics to address the role of UPF2, a core NMD component, in the development, function and regeneration of the liver.

In summary, using biochemistry, mouse genetics, and clinical tumor specimens we have found that SIRT1, a diet-responsive gene, is a regulator of β-catenin and has a tumor suppressive function.

For this purpose, we used mouse genetics focusing on nerve development and nerve homeostasis.

In the present study, we use mouse genetics, retinoic acid (RA) treatments and chick electroporation to investigate the mechanism of segmentation at r6/r7, a caudal hindbrain boundary that does not require Krox20.

Mouse genetics to date has contributed much to what we know about the genetic epidemiology of bone fragility and associated phenotypes, such as BMD and bone microarchitecture.

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