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Oligonucleotide primer sequences of the mouse genes studied were the following.
The oligonucleotides primers sequences of the mouse genes studied (Table 2) were designed with Oligo 4 software and synthesized by Eurogentec (France).
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In this particular case we compared WT and KO mice values for all the genes studied in each tissue separately.
As a result, many phenotypes have not been detected, and consequently, the full biological function of many genes studied using knockout mice is significantly underreported.
Lexicon, for example, is analysing 5,000 mouse genes and studying the physiology and behaviour of mice to discover novel drug targets in a number of areas, including cognitive and neurodegenerative disorders.
Since the set of 36 mouse gene products studied is highly replicated in the human genome (with highly similar sequences for all 36 and full-length similarity for 28), we suggest that these 36 genes will include genes relevant both for mouse and human ESC differentiation.
Gene indexing is an MGI-specific curation function that involves identifying which mouse genes are being studied in an article, then associating the appropriate gene symbols with the article reference number in the MGI database.
The global topological properties of the human and mouse gene coexpression networks studied here are very similar but the specific architectures that underlie these properties are drastically different.
Mouse gene knockout studies indicate that all four CatSper subunits are required to mediate functional Ca2+-selective sperm currents necessary for sperm hyperactivation [12] [14], [21].
These include Eurexpress (8) a transcriptome-wide mouse gene expression study that shares the same anatomy ontology.
The results of mouse gene knockout studies disagree about the degree to which mice lacking these receptors learn to drink sweeteners if given periods of exposure to sweetened water.
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