Sentence examples for mouse fibroblasts have from inspiring English sources
To test whether expression of AtCRT1a or CRT3 in the crt−/− mouse fibroblasts have regained their adhesive potency we determined the cell shape, which is conventionally examined to assess cell spreading, and therefore the level of cell adhesion [4].
ClCN4 wild-type and null mouse fibroblasts have been described elsewhere (Mohammad-Panah et al, 2009).
Studies in mouse fibroblasts have shown that c-Src kinase is required for ERK5 activation in response to hydrogen peroxide.
Migration-retarded PTP-PEST deficient mouse fibroblasts have exaggerated membrane PTP-PEST deficient leading edge and long, unretracted tails in the rear that are mouseted by enhanced Rac1 activity and decreased RhoA activity, respectively [46].
A particularly striking example was the demonstration in 2003 by the Campisi group that primary mouse fibroblasts have an indefinite proliferative lifespan in 3% oxygen, the amount found in the capillaries feeding the tissues, but greatly shortened ones under normal in vitro culturing conditions, i. e., 20% oxygen [ 1].
Comparison of the effects of 20-nm silicon dioxide (SiO2) and zinc oxide (ZnO) NPs on mouse fibroblasts has shown that they differ in the mechanisms of toxicity.
For example, OPN from ras-transformed mouse fibroblasts has less phosphorylation than OPN from differentiated mouse osteoblasts and can bind more readily to MDA435, a breast cancer cell line [19].
Overexpression of Fe65 in mouse fibroblasts has been shown to block cell growth by inhibiting the activation of a key S phase gene, the thymidylate synthase (TS) gene [37].
Furthermore, late generation mTerc-/ WRN -/- mouse embryonic fibroblasts have an increased load of DNA damage and replicative senescence, properties similar to that observed in human WS fibroblasts.
41, 42 Tumors derived from PERK−/− mouse embryonic fibroblasts have limited ability to stimulate angiogenesis.
The generation and maintenance of mouse embryonic fibroblasts have been described previously [ 30].
