The mice experiments followed internationally recognized guidelines and were approved by the Government of Upper Bavaria.
These experiments followed hot on the heels of "marathon mice", which hit the headlines in 2004 after researchers genetically engineered the lab animals by tweaking a gene called PPAR-delta.
All experiments followed NIH guidelines for th ecare and use of mice.
For mouse experiments, one-way ANOVA followed by Dunnett's multiple comparison test, one-way ANOVA followed by Tukey's test and Student's t-test were performed.
We analyzed cells from these mice by metabolic labeling in a pulse chase experiment, followed byimmunoprecipitation (Figure 3).
In follow-up mouse experiments that directly compared regular and modified beta cells, most of the gene mutations panned out.
All mouse experiments were approved by the Stanford Administration Panel on Laboratory Animal Care and we strictly followed their specific guidelines.
All mouse experiments were done in accordance with protocols approved by the Institutional Animal Care and Use Committee of MSKCC and followed National Institutes of Health (NIH) guidelines for animal welfare.
contributed to humanized mouse experiments.
