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These mouse experiments confirmed that the knockdown of candidate genes induced aneuploidy in murine hematopoietic cells (Lin-negative) re-isolated from primary recipients (Fig 4A and B).
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Although LysMcre is supposed to be expressed by a small population of DCs [44], CD11ccre mice experiments confirm that conventional DCs do not significantly contribute to IFN-β production.
An equivalent mutation was subsequently created for mouse PLCζ (PLCζH435P) [ 88]; murine experiments confirmed that this mutation caused major structural changes to the PLCζ protein, resulting in functional inactivation.
The mouse experiments thus confirm that metamers can be used to selectively modulate melanopsin.
Combined EEG/calcium imaging experiments confirmed that neurons in mutant mice have abnormally high firing and synchrony during sleep/rest.
Initial experiments confirmed that normal, immunocompetent BALB/c mice did not form lung tumors.
The experiments confirmed the effective dose in mice to be in the range of 30 100 mg·kg−1 [ 78].
Both experiments confirmed the absence of any retroviral involvement in the diseased mouse livers.
A final set of experiments confirmed the effectiveness of metformin in vivo in wild-type C57BL/6 mice.
Subsequent experiments confirmed exactly that.
Decades of experiments confirmed this.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com