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G.S. and S.V. supervised mouse experiments and animal welfare approval.
A.R.-G., O.R., V.V.S. and J.W. performed and evaluated cell culture experiments, C-Y.Y., R.G., Y.I. and K.K. performed and evaluated the mouse experiments and M.K. and M.L.S. designed and wrote the paper.
Differential gene expression was observed for these loci in minus-lens-induced myopia mouse experiments and human ocular tissues.
Examples of reductionist studies that have driven much of our understanding of biological processes associated with complex phenotypes like disease include the knockout mouse experiments and in vitro cytokine treatment to assess the effects of gene-specific perturbations on cell or tissue biology.
YW performed and interpreted mouse experiments and edited the manuscript.
MJB participated in the mouse experiments and drafting of the manuscript.
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When applied to the genesets from the published data including an in vitro experiment, an in vivo mouse experiment, and an experiment with human tumor samples, Literature Lab correctly identified known biological processes occurring within each experiment.
Strikingly, these patterns capture both dose effects in the mouse experiment and strain differences in the macaque experiment.
Live-mouse experiments and live-virus experiments were performed in Biosafety Level 3 facilities following governmental and institutional guidelines.
Details of individual mice, experiments, and the statistical treatment.
KRV performed all mice experiments and analyzed data.
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