Sentence examples for mouse erythroid cell from inspiring English sources
Considering the number of human ES cell lines that have been established so far, the intensive testing of a number of these lines for erythroid potential may allow the establishment of human erythroid cell lines similar to the mouse erythroid cell lines described here.
We further applied dCaP to detect differential TAL1 occupancy in response to GATA1 restoration in two mouse erythroid cell lines.
We further show in the mouse dataset that dCaP captures genomic regions showing significant signal variations for TAL1 occupancy between two mouse erythroid cell lines.
The target ChIP data and the supporting data are generated from the same mouse erythroid cell line with restoration of GATA1 function (G1E-ER4).
Applying the method to GATA1 restoration in mouse erythroid cell line, we detected many new GATA1-binding sites using GATA1 co-occupancy data.
We further applied dCaP Test 2 (dCaP-T2) to detect differential TAL1 occupancy before and after restoration of GATA1 in two mouse erythroid cell lines (G1E, G1E-ER4) reported in Wu et. al [ 15].
Whyatt D, Lindeboom F, Karis A, Ferreira R, Milot E, Hendriks R, et al. An intrinsic but cell-nonautonomous defect in GATA-1-overexpressing mouse erythroid cells.
Correlation between gene silencing and localisation to transcriptionally repressive heterochromatic compartments has been reported in mouse cycling lymphocytes [55], [56], [57], human and mouse erythroid cells [58], [59], [60] and retinoblastoma cells [61].
Furthermore, we observe that the boundaries of the topological domain, which contains the β-globin locus, are easily observed in mouse erythroid cells.
A molecular colony technique recently developed by Gavrilov et al. [ 17] investigated multicomponent interactions among remote enhancers and active β-globin genes in mouse erythroid cells.
In addition, RNA-interference-mediated knockdown of seven abundantly expressed lncRNAs in mouse erythroid cells inhibited terminal erythroid differentiation [ 54], raising the possibility that a large number of tissue-specific lncRNAs are necessary for cell identity programs.
