Reproductive Toxicology found that even low-level exposure to BPA led to the mouse equivalent of early puberty for females.
Circulating red blood cells essentially synthesized β-minor globin, the mouse equivalent to human γ-globin.
"During the mouse equivalent of childhood and adolescence they were becoming rapidly obese," Dr. Majzoub said.
The mouse equivalent of a "smoker's cough" was almost completely blocked when mice inhaled menthol and tobacco irritants together.
This dose is the mouse equivalent of drinking one soda per day, which about half of Americans do, Goncalves said.
One was young, the equivalent of a human 20-year-old, while the other was the mouse equivalent of an 80-year-old.
The beneficial effect was especially pronounced in those animals that exercised in the afternoon (or mouse equivalent).
To settle that question, Elias and Chupp went back to mice, genetically engineering them to have either none of the mouse equivalent of YKL-40, or too much.
The Wisconsin researchers report that they saw no change in the mouse equivalent of sirtuin during caloric restriction, a finding that if true could undercut Sirtris's strategy of looking for drugs that activate sirtuin.
This dystopia may be closer than Winterson expected: the journal Nature reported last week that a drug, rapamycin, extended the life of mice by up to 14%, even if it was administered at the mouse equivalent of 60 years old.
