The graphical portrayal of Nazis as cats, and Jews as mice, enables a surprisingly human reading of what is an invaluable story of survival.
Both lesion profile and PET blot PrPSc distribution in Tg 338 mice enabled a clear differentiation between the S83 isolate, atypical scrapie, and BSE in sheep.
The implantation into enhanced GFP expressing mice enabled a clear fluorescence-based discrimination of implanted tumour cells from enhanced GFP-positive host cells both on tissue sections and by fluorescence-activated cell sorting analysis (Fig. 1C).
This species independent binding of ESTA-1 to E-selectin, at least in human and mouse, enables thorough characterization of this ligand in a variety of mouse disease models for possible biomedical application.
The use of this mTert-GFP reporter mouse enables the demonstration of telomerase expression at a single-cell level, overcoming the problems associated with conventional immunohistochemistry.
However, it should accommodate the mouse, enable leg clearance, and have an adjustable height and tilt mechanism.
Diaphragm-derived cells are easy to prepare and have the advantage over MEFs that they can be prepared from a single adult mouse, enabling individual genetically different animals to be studied genetically and functionally at the cellular level.
In the present study, we showed that the Sox10-IRES-Venus mouse enabled the non-destructive visualization and understanding of the morphogenesis during the development of the inner ear.
The hph-1 mouse model of BH4 deficiency and the GCH-Tg mouse enabled us to make this comparison, and treatment of these mice with MTX (three ip injections of 2 mg/kg) resulted in a dramatic attenuation of DHFR activity.
We describe different gene targeting methods: the generation of "conventional" knock-out mice enables us to delete a gene of interest in every cell of the body.
