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Experiments here first examined mouse eggs, addressing the question of whether ITGB1 (as the partner to ITGA9) is the primary integrin in mouse eggs that mediates egg interactions with ADAM2.
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Scientists have created mouse eggs from stem cells and used them to make healthy baby mice.
Wang Q, Racowsky C, Deng M. Mechanism of the chromosome-induced polar body extrusion in mouse eggs.
Tahara, M. et al. Dynamics of cortical granule exocytosis at fertilization in living mouse eggs.
They would then implant the genes required to make those antibodies into the cells of mouse eggs.
Treatment of mouse eggs with a membrane-permeable zinc chelator reduces intracellular zinc availability and is sufficient to induce egg activation10,11,17.
Tarkowski, A. K. & Wroblewska, J. Development of blastomeres of mouse eggs isolated at the 4- and 8-cell stage.
Deng, M., Gao, J., Suraneni, P. & Li, R. Kinetochromosomepolewardchromovementolewarduringment during anaphase of meiosis II in mouse eggs.
The scientists then took immature eggs from newly born mutant mice and inserted their nuclei into normal mouse eggs.
Researchers also used the technique successfully on faulty human mtDNA, inserted into mouse eggs.
For the study, the researchers used a set of new imaging techniques to count and map the positions of individual zinc atoms in mouse eggs.
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