Sentence examples for mouse effector cells from inspiring English sources

The nonclinical pharmacological assessments have shown that codrituzumab elicited antibody-dependent cellular cytotoxicity through human peripheral blood mononuclear cells (PBMCs) as well as mouse effector cells against GPC3-expressing human HCC and hepatoblastoma cell lines in vitro.

Recently, it was shown that oxidized lipoproteins inhibited FOXP3 expression and Treg function of mouse effector cells in vitro[15].

In addition, we showed that human IgA EGFR mediates efficient cytotoxicity ex vivo by mouse effector cells expressing human FcαRI.

IgA2 EGFR showed stronger ADCC activity than IgA1 EGFR in vitro with both human and mouse effector cells (Fig 1; Dechant et al, 2007).

To study whether human IgA EGFR mediate anti-tumour activity by mouse effector cells ex vivo we used whole blood from G-CSF-stimulated FcαRI Tg and WT control mice as effector cells.

To study whether scIgG-T lost Fc-mediated immune cell effector function in vivo, we studied the effect of trastuzumab and scIgG-T on the infiltration of mouse immune effector cells in the xenograft tumors.

We used CTLs from TCR-transgenic OT-I mice as effector cells, which recognize the ovalbumin-derived peptide SIINFEKL in an H2Kb-restricted manner [ 33].

Standard 4-h Cr-release assays were performed using pooled granulocytes from 14 G-CSF-injected or 15 naïve SCID mice as effector cells (E) and S-YU cells as targets (T) at E/T ratios of 50 1, 100 1 and 200 1.

For mouse CIK cells, effector cells were spleen CIK cell culture harvested at 7 or 14 days.

Each mouse received 105 pulsed DCs given s.c. on day 0. On day 2, all mice received T effector cells transduced with Tyr-TCR/firefly (f Luciferase vector intravenously.

The receptor ligand binding of NKG2A to the MHC class Ib antigen HLA-E (human leukocyte antigen E; Qa-1b in mice) suppresses effector cell cytotoxic activity.