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If, say, the mouse develops a disease, the indication is that the gene is related to the condition.
The mouse develops a developmentally and functionally distinct, non-canonical beige fat cell type as an adaptation to cold ambient temperature.
Objective The STR/ort mouse develops a naturally occurring osteoarthritis of the femorotibial joint that provides a model with which to establish the time course of biochemical changes taking place in articular cartilage in the disease.
This mouse develops a patchy, chronic colitis similar to human Crohn's disease.
In addition, in both models, the DBA/1 mouse develops a severe but acute and self-limited type of arthritis.
For example, the lag mouse develops a lymphoproliferative disorder that resembles systemic lupus erythematosus (SLE) due to a failure to properly process the precursor mRasGRP1 transcript [ 6].
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When a mouse developed a palpable tumor, it was randomly assigned to one of 4 groups.
This mouse developed a lump on its back at 25 weeks of age.
One mouse developed a 5 mm nodule by 15 months of age.
In addition, two studies demonstrated that a compound Dok1/Dok2 knockout mouse developed a CML-like disease [ 61, 62].
Subsequently, these mice develop a lymphoproliferative syndrome that culminates with the development of lymphomas displaying features typical of human DLBCL.
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