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To reveal the importance of SNAP-23 function in mouse development, we generated Snap23-null mice by homologous recombination.
To characterize the activity of p66 and assess its importance in mouse development, we have made loss of function mutants in the mouse p66α gene (mp66α, official name Gatad2a, MGI 2384585).
To test the ability of Tbx1 to suppress Smad1 signaling during mouse development, we have used a mouse transgenic line, named COET (for Conditional OverExpression of Tbx1), expressing Tbx1 upon Cre-mediated recombination [23].
To further evaluate the putative role of Dmrt2 in LR asymmetry patterning in mouse development, we studied the expression of left-sided specific markers in dmrt2 null mutants [24].
To further evaluate the significance of RASSF9 gene expression for normal mouse development, we determined the expression profiles of RASSF9 gene in various organs of WT mice at one or two weeks old.
To identify candidate genes that may be involved in the gene network controlling mouse development, we used genes from the extracted seed-network (ESN; mouse homologs of fly RDGN genes whose pairwise expression correlation coefficients were >|0.65| in at least one dataset) to query large-scale gene expression datasets of the developing retina (I IV).
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In order to define its potential role in mouse sexual development we generated mice lacking Maestro using gene targeting.
To understand the functional significance of LMO4 in mouse retinal development, we conditionally ablated a floxed LMO4 allele in the retina using the Pax6 alpha enhancer driven Cre recombinase [8].
Based on results presented here and previously published for mouse pyloric development, we propose a model for a molecular interaction network controlling pyloric development.
Since we performed our expression analysis during mouse embryonic development, we were able to compare our data with previously published data on the function of UCEs as long-range enhancers in mouse embryonic stages [ 8].
In order to compare our results to published data on mouse molar development, we present two summary tables for gene expression in the mesenchyme (Table 1) and epithelium (Table 2).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com