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We observed that a bitransgenic mouse derived from line 51 became tachypneic and had an apparent large tumor burden on MRI after being administered a dox-containing diet for 17.5 weeks (data not shown).
A success story for mapping of spontaneous mutations is the SKG mouse, derived from a BALB/c breeding.
Finally, human, chimp, and mouse derived from a common Euarchontoglires intermediate of 39 protochromosomes that have been shaped from the n = 30 Amniote clade ancestor with 24Cfis 15Cfus.
Here, we utilize ESCs containing this reporter, and a transgenic reporter mouse derived from them, to explore the nature of the ground state and investigate the cell-intrinsic role of LIF in this defined context.
However, deficiency of MBD2 suppresses intestinal tumorigenesis in an Mbd2-knockout mouse derived from a lineage with an autosomal-dominantly inherited predisposition to multiple intestinal neoplasia (Min) (Sansom et al, 2003).
Genomic DNA samples extracted from mouse (a female F1 hybrid mouse derived from crossing C57BL/6 J and SPRET/EiJ) liver were used to generate Illumina Paired-End precapture libraries according to the manufacturer's protocol (Agilent).
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Figure 2: Cloned embryos and mice derived from urine-derived cell nuclei.
Humpherys, D. et al. Abnormal gene expression in cloned mice derived from embryonic stem cell and cumulus cell nuclei.
To recapitulate the cellular and molecular context of ATRX deficiency in human glioma, we extracted primary mNPCs from the brains of mice derived from Tp53−/− and floxed Atrx (Atrx fl) parental strains, culturing them in stem-like (neurosphere) conditions.
Animals were C3Hf/Sed mice derived from our defined flora mouse colony.
(H) Chimeric mice derived from injecting C57/B6 8 cell embryos with NPG-ESCs.
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Justyna Jupowicz-Kozak
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